This study demonstrated the potential use of pregelatinized starches, especially those obtained from yucca and corn as direct compression filler-binders. Conversely, rice starch showed a high elasticity, and friability, low compactibility, which are undesirable for direct compression. A pharmaceutical composition comprising a therapeutically effective amount of the solid form of claim 1, 2, 3, or 4, and a pharmaceutically acceptable excipient. These two materials showed compact disintegration slower that Starch 1500. Their onset of plastic deformation and their strain rate sensitivity was comparable to that of Starch 1500. This basic corn starch can also be developed into specialty starch products with enhanced functional properties. It is highly digestible and primarily used in food and beverage products such as soups, beverages, baby food, and bakery products. The starch slurry is then filtered and dried to produce a fine-powdered starch. The maximum hardness of 23.651 kp (F3) where Prosolv 50 MSCC contains microcrystalline.
These starches are produced from potato, wheat and arrowroot. Although Spress B820 is supposed to render starch directly compressible. However, yucca starch and corn starch showed an irregular granule morphology, better compactibility and compressibility than Starch 1500. Pregelatinized starch is a carbohydrate that is cooked and dried, then converted into powder or flaked form. This material had the lowest particle size, and porosity and largest density and best flow. Read the latest magazines about Starch, Pregelatinized 69 and discover magazines on. The aim of this study was to evaluate the powder and tableting properties of pregelatinized starches obtained from yucca, corn and rice and compare those properties with those of Starch 1500.
It is known that the tableting performance of excipients could be affected by their source. Pregelatinized starch is widely used as a pharmaceutical aid, especially as a filler-binder.
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